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Hippocampi Posterior Limbic System

Hippocampus

Functions

Encoding, retention and retrieval of spatial and episodic experiences S; memory S, above all episodic and autobiographic S, but not procedural, and only in part semantic (controversial, S, S, S); learning, recognition S

Encoding and retrieval of relational information in visual short-term memory S

Spatial (CA3 subregion, S) and contextual learning and memory S, continuous encoding of ongoing experience, categorization S, pattern separation and pattern completion S

Behavioral regulation and inhibition (e.g. of food intake for body weight regulation) S

Speech comprehension through mnemonic encoding of narrative information S
Disorders (Hippocampus)

Amnesia, PTSD S and other stress-related disorders S; Alzheimer's Disease S, Depression S, S, Anxiety Disorders S, Bipolar Disorder S, S, Dissociative disorders S, Obesity S, Tourette Syndrome S, Cushing's syndrome S, Multiple Sclerosis S; Huntington's Disease (posterior) S

Dentate gyrus

Functions

Memory formation; regulation of stress responses S, neurogenesis even in adults S

Geometry of the environment S, spatial pattern separation during learning S

Disorders

PTSD S, stress-related disorders (above all due to the suppression of neurogenesis by exposure to high levels of corticosterone S), Depression S, S, S (cognitive aspects S), Déjà vu, Epilepsy S, Alzheimer's Disease S, S
hippocampus

Sources: Rita Carter: "Mapping the Mind" (upper left and right), Thinkquest (below).

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